Microcrystalline Cellulose Spheres
Chemically Inert Carrier
VIVAPUR® MCC Spheres consist purely of microcrystalline cellulose, making them extremely robust and chemically inert. They are, therefore, excellently suited as a carrier system. API-layered VIVAPUR® MCC Spheres can be filled into capsules and compacted into tablets.
They possess a tight particle size distribution, allowing for better control and higher batch-to-batch consistency of API release profiles. The particle size uniformity minimizes segregation risks during encapsulation or tableting, permitting greater API content uniformity. Additionally, it is possible to apply different APIs in various concentrations and combine the coated spheres in a single unit dose.
VIVAPUR® MCC Spheres are available in a wide range of particle sizes.
Grade | Size | Main Application | ||
(mesh) | (µm) | |||
VIVAPUR® MCC Spheres 100 | 70 – 140 | 100 – 200 | - Water insoluble carrier | |
VIVAPUR® MCC Spheres 200 | 45 – 70 | 200 – 355 | ||
VIVAPUR® MCC Spheres 350 | 35 – 45 | 355 – 500 | ||
VIVAPUR® MCC Spheres 500 | 25 – 35 | 500 – 710 | ||
VIVAPUR® MCC Spheres 700 | 18 – 25 | 710 – 1000 | ||
VIVAPUR® MCC Spheres 1000 | 14 – 18 | 1000 – 1400 |
Multiparticulate systems become have increasingly
important in state-of-the-art formulation development.
VIVAPUR MCC SPHERES® are particularly beneficial as
a carrier for multiple-API dosage forms and controlled
release formulations.