Microcrystalline Cellulose and Carboxymethylcellulose Sodium
Dispersible Cellulose
VIVAPUR® MCG is a synergistic, co-processed composite consisting of microcrystalline cellulose (MCC) and sodium carboxymethylcellulose (Na-CMC). It is a unique suspending and emulsifying agent, which facilitates a wide range of liquid dosage forms. Due to its extraordinary stabilizing mechanism, VIVAPUR® MCG can be used with a broad variety of active pharmaceutical ingredients (APIs), offering the opportunity for new applications and line extensions for existing products.
VIVAPUR® MCG is a free flowing powder. After activation, MCG builds an opaque-white dispersion which masks insoluble particles, giving the suspension a homogenous appearance. The dispersed VIVAPUR® MCG is distinguished by an odorless and tasteless, smooth but not slimy mouth feel, and handles flavors well. Upon agitation, MCG dispersions show a time-dependent decrease in viscosity and become liquid. A complete, also time-dependent, regeneration of the viscosity takes place during a subsequent rest period. This thixotropic behavior allows:
| NaCMC (%) | Particle Size | Viscosity | Main Application |
VIVAPUR® MCG 581 P | 8.3 – 13.8 | >250 µm (60 mesh): | 72 – 168 | For "ready-to-use" suspensions and emulsion prepared with high shear forces. |
VIVAPUR® MCG 591 P | 8.3 – 13.8 | >250 µm (60 mesh): | 39 – 91 | |
VIVAPUR® MCG 611 P | 11.3 – 18.8 | >250 µm (60 mesh): | 50 – 118 | For reconstitutable dry suspensions. |
VIVAPUR® MCG 811 P | 11.3 – 18.8 | >250 µm (60 mesh): | 2400 – 5600 | Highly effective dispersible cellulose grade for a variety of suspensions, emulsions, and spray applications. |
VIVAPUR MCG® is a free-flowing powder consisting of
microcrystalline cellulose (MCC) and sodium
carboxymethyl cellulose (Na-CMC).