Select filler/binder grade according to API's particle size distribution. PROSOLV® EASYtab, add more disintegrant and lubricant, if needed
Use VIVASOL® extragranularly and other disintegrants in the granules.
Use part of the binder extragranularly.
Use part of the binder extragranularly. Use VIVASOL® extragranularly and other disintegrants in the granules.
Use part of the binder extragranularly. Use VIVASOL® extragranularly and other disintegrants in the granules.
When using PROSOLV® EASYtab SP , add more disintegrant and lubricant, if needed.
When using PROSOLV® EASYtab SP , add more disintegrant and lubricant, if needed.
Alternatively, use a blend of PROSOLV® SMCC 50 LD (70%) and EMCOMPRESS® Anhydrous (30%) in the ribbon.
Alternatively, use a blend of PROSOLV® SMCC 50 LD (70%)and EMCOMPRESS® Anhydrous (30%) in the ribbon.
Alternatively, use a blend of PROSOLV® SMCC 50 LD (70%) and EMCOMPRESS® Anhydrous (30%) in the ribbon, use binder intra- and extragranularly.
Alternatively, use a blend of PROSOLV® SMCC 50 LD (70%) and EMCOMPRESS® Anhydrous (30%) in the ribbon, use binder intra- and extragranularly.
For the Recommended Excipients and PROSOLV® EASYtab SP formulations, geometric blending is advised to ensure Content Uniformity.
For the Recommended Excipients and PROSOLV® EASYtab SP formulations, geometric blending is advised to ensure Content Uniformity.
When developing a formulation for an immediate release tablet, critical attributes of the active ingredient, including concentration, compactability, flowability and solubility typically guide excipient selection. They also determine the type of manufacturing process that will be used in commercial production. This tablet formulation guide was developed to help simplify and optimize the excipient and manufacturing process selection using those four active ingredient attributes.
DOSE
FLOWABILITY
COMPACTABILITY
SOLUBILITY
RESET
Select filler/binder grade according to API's particle size distribution. When using PROSOLV® EASYtab, add more disintegrant and lubricant, if needed.