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PRUV®
Sodium Stearyl Fumarate
Beyond Tableting Lubrication
PRUV® is a tablet lubricant designed for formulations in which other lubricants lead to formulation and/or manufacturing challenges. As opposed to the frequently used lubricant, magnesium stearate, PRUV® offers the following advantages:
- High degree of API compatibility*
- Robustness to over-lubrication
- No adverse effect on bioavailability
- Improved appearance of effervescent solutions.
PRUV® helps to accelerate product development and is particularly well suited for high-speed direct compression of tablets.
*Reported API incompatibilities with magnesium stearate include: Azathioprin, Cefaclor, Cilazapril, Clopidogrelacetate, Dicofenac, Fosinopril, Ibuprofen, Ketorolac, Levofloxacin, Nifedipine, Omeprazole, Ramipril, and Trandolapril.
Sodium Stearyl Fumarate2
Ph. Eur., NF, JPE, FCC
Specification | PRUV® | PRUV® CG |
|---|---|---|
Specific Surface Area | 1.2 - 2.0 m2/g* | 0.3 - 1.0 m2/g* |
pH | about 8.5 | about 8.5 |
Saponification Value | 142.2 – 146.0 | 142.2 – 146.0 |
Moisture | < 5.0 % | < 5.0 % |
Solubility | 0.5 mg/100 mL at 25 °C | 0.5 mg/100 mL at 25 °C |
Melting Point | 224 – 245 °C (dec.) | 224 – 245 °C (dec.) |
Downloads
Brochure PRUV®
PRUV® is a tablet lubricant specifically designed for
formulations in which other lubricants lead to formulation and/or manufacturing challenges.
Watch our Product Video PRUV®
