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VIVACOAT® protect E
Ready-to-Use High-Functionality Coating System
Enteric Coating, Moisture Barrier
VIVACOAT® protect E is a white Ready-to-Use enteric coating system based on the globally accepted Metha-crylic Acid-Ethyl Acrylate copolymer (1:1).
VIVACOAT® protect E dissolves at pH values exceeding 5.5. It was developed to protect acid-sensitive APIs against gastric fluids. Likewise, it protects the stomach against irritating actives by delaying drug delivery until the dosage form reaches the small intestine.
The VIVACOAT® protect E system requires no neutralization. This enables an easy one-step reconstitution in water.
Due to the high polymer content of the coating suspension, VIVACOAT® protect E provides short process times.
VIVACOAT® protect E is the ideal solution for delayed release oral dosage forms. Time savings in developement and production are achieved by a simple, fast and robust coating process. Also beneficial are reduced raw material inventory and QC requirements.
We recommend VIVACOAT® PS-1P-041 as sub-coat formulation, if the active ingredient has to be separated from the enteric polymer. For colored tablets, pigmented VIVACOAT® A formulations are ideally suited to be used as a top-coat.
For technical support in lab- and production scale please reach out to JRS Pharma global technical team.
Contact us to obtain your sample of VIVACOAT® protect E .
Product Performance Profile
Recommended Process Parameters
Recon Level [%] | Inlet Temp [°C] | Tablet Bed Temp [°C] | Exhaust Temp. [°C] | Total Spray Rate [g/min] | Pan Speed [rpm] | |
|---|---|---|---|---|---|---|
Fully Perforated Pan, Batch size 800 g | 20 | 58 | 30 - 33 | 35 - 38 | 2 - 3 | 7 - 9 |
Conventional Pan, Batch size 2000 - 3000 g | 20 | n.a. | 35 - 38 | n.a. | 10 - 15 | ca. 5 |
Semi Perforated Pan, Batch size 18 - 20 kg | 20 | 50 - 60 | 32 - 34 | 46 - 49 | 55 - 60 | 3 - 4 |
Fully Perforated Pan, Batch size 18 - 20 kg | 20 | 45 - 55 | 30 - 33 | 42 - 44 | 60 - 70 | 3 - 4 |
Fully Perforated Pan, Batch size 100 - 120 kg | 20 | 45 - 55 | 30 - 33 | 42 - 44 | 180 - 190 | 2 - 3 |
Fully Perforated Pan, Batch size 300 - 400 kg | 20 | 45 - 55 | 30 - 33 | 42 - 44 | 700 - 800 | 1 - 2 |
Downloads
Brochure VIVACOAT® protect E
VIVACOAT® is a robust film coating system which
shows outstanding performance in both laboratory and
production equipment.
