Poly Vinyl Alcohol
Coating Polymer
Poly vinyl alcohol is a well-established polymer in the pharmaceutical industry. Due to its unique properties, it is used in various applications. The most widely used applications are tablet coating and wet granulation, but PVA also plays an important role in solubility enhancement, transdermal patches and emulsions.
VIVAPHARM® PVA 05 fine is a water soluble synthetic polymer.
It is synthetized by polymerization of vinylacetate and subsequent partial hydrolysis.
Physico-Chemical Properties
• Excellent Film Former
• High Moisture & Gas Barrier
• Highly Adhesive at Low Viscosity
• Soluble in Water
• High Purity
• Chemically Stable
• Non-toxic
Applications
• Tablet Coating
• Moisture and Oxygen Barrier
• Wet Granulation
• Hotmelt Extrusion
• Thickener
• Emulsions
• Transdermal Patches
Tablet Coating:
• Excellent Moisture Barrier Performance
• Good Odor Masking Ability
• Oxygen Barrier
• Low Viscosity Enabling High Solid Content in Coating
• Suspensions
• Good Adhesion to Tablets
Wet Granulation:
• High Productivity because of Low Viscosity
• High Adhesive Strength Enables Low Binder
• Concentration
• High Tablet Hardness and Low Friability Prevention of Capping especially at High Drug Loads
• No Peroxides
Grade | Degree of Hydrolysis (mol - %) | Viscosity (4 %) [mPas] | Main Application |
---|---|---|---|
VIVAPHARM® PVA | 85 - 89 | 4.6 - 6.0 | Tablet coating, wet granulation |
The main characteristics of VIVAPHARM® PVA fine 05 are degree of hydrolysis and degree of polymerization. Solubility is controlled by the degree of hydrolysis and is highest at 88 mol% hydrolysis.